Hyaluronic Acidobservational1977
[Histochemical study of the ground substance in chordoma].
Annales d'anatomie pathologique
confidence
Key findings
Histochemical demonstration of neutral substance, acid mucosubstances, sialic acid, and probable hyaluronic acid in chordoma matrix
View source on PubMed (PMID 1008324) ↗
- Sample size
- 1 chordoma and one recurrence
- Population
- Chordoma tumor tissue and recurrence (histochemical study)
- Dosing
- not applicable
- Duration
- not_reported
- Route
- not applicable
- Blinding
- not_reported
- Controls
- none
- Drug class
- glycosaminoglycan
Full abstract
Using a series of histochemical reactions, the authors studied the intercellular substance of a chordoma and of one of its recurrences, and were able to demonstrate the presence of neutral substance, of acid mucosubstances with carboxyl groups and sulphated groups. The presence in the intercellular matrix of the chordoma of sialic acid was shown, as well as the probable presence of hyaluronic acid.