Collagen Peptidesobservational1999
HPLC method to characterize cyanogen bromide collagen fractions containing pyridinoline groups.
Bollettino della Societa italiana di biologia sperimentale
confidence
Key findings
HPLC method to separate CNBr collagen peptides and characterize peptide bonds and pyridinoline groups; analytical only, no clinical endpoints.
View source on PubMed (PMID 10327703) ↗
- Sample size
- N/A
- Population
- N/A (analytical methods paper)
- Dosing
- N/A
- Duration
- N/A
- Route
- N/A
- Blinding
- not_reported
- Controls
- none
- Drug class
- supplement
Full abstract
The HPLC method here described allows to separate CNBr collagen peptides within 2.5 h by reversed phase and gradient elution. The method is useful to determine both peptide bond and pyridinoline groups by absorbance spectophotometry. The fractions can be recovered and then submitted to other characterization techniques.