ResveratrolAnimal model2008

Fate of resveratrol and piceid through different hop processings and storage times.

Journal of agricultural and food chemistry

confidence

Key findings

Analytical study on resveratrol and piceid content in hop products; no clinical or biological endpoints reported.

View source on PubMed (PMID 18163557) ↗

Sample size
Not reported
Population
Not applicable (analytical study of hop processing and storage)
Dosing
Not applicable
Duration
1 year storage
Route
Not applicable
Blinding
not_reported
Controls
not_reported
Drug class
polyphenol
Full abstract

Trans-Piceid and trans-resveratrol contents of hop cones, hop pellets, CO2 extracts, and spent hop from American varieties (harvest 2004) were determined by reverse-phase high-performance liquid chromatography-atmospheric pressure chemical ionization-tandem mass spectrometry [RP-HPLC-APCI(+)-MS/MS]. Pelletization induced strong stilbene degradation in some cultivars. Similarly, 1 year of storage at 4 degrees C led to a huge loss of trans-piceid, especially in the case of hop cones (much faster than in model media, although well protected from light and oxygen). Therefore, after 8 months of storage, the overall stilbene content was in the same range whatever the conditioned form. Absent in fresh hop cones or pellets, cis-resveratrol was released from cis-piceid in all stored samples. On the other hand, no delta-viniferin was detected despite it is present in light-protected model media spiked with trans-piceid. Because supercritical carbon dioxide proved inefficient for recovering resveratrol and piceid from pellets, spent hop emerged as the most interesting material for subsequent specific stilbene extraction.

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