NAD+animalAnimal model2012

The electrochemical regeneration of NAD(+) revisited.

Biotechnology and bioengineering

confidence

Key findings

Electrochemical regeneration of NAD+ achieved 99.97% yield (3000 cycles), deactivation time-dependent, not cycle-dependent; suitable for biotech.

View source on PubMed (PMID 18581294) ↗

Sample size
N/A
Population
N/A (electrochemical study)
Dosing
N/A
Duration
N/A
Route
electrochemical
Blinding
not_reported
Controls
none
Drug class
coenzyme
Full abstract

An actual yield of 99.97% (i.e., 3000 potential regenerating cycles) has been obtained for the electrochemical regeneration of NAD(+). The deactivation of the coenzyme is not related to the number of cycles; it is only time dependent. For biotechnological applications, these results show that electrochemical regeneration can compete with enzymatic regeneration for selective oxidation by dehydrogenases.

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