The electrochemical regeneration of NAD(+) revisited.
Biotechnology and bioengineering
confidence
Key findings
Electrochemical regeneration of NAD+ achieved 99.97% yield (3000 cycles), deactivation time-dependent, not cycle-dependent; suitable for biotech.
View source on PubMed (PMID 18581294) ↗
- Sample size
- N/A
- Population
- N/A (electrochemical study)
- Dosing
- N/A
- Duration
- N/A
- Route
- electrochemical
- Blinding
- not_reported
- Controls
- none
- Drug class
- coenzyme
Full abstract
An actual yield of 99.97% (i.e., 3000 potential regenerating cycles) has been obtained for the electrochemical regeneration of NAD(+). The deactivation of the coenzyme is not related to the number of cycles; it is only time dependent. For biotechnological applications, these results show that electrochemical regeneration can compete with enzymatic regeneration for selective oxidation by dehydrogenases.