Vitamin Cobservational2012

Fluorimetric and phosphorimetric characteristics of several vitamins.

Talanta

confidence

Key findings

Analytical study of fluorescence and phosphorescence of 14 vitamins; no clinical or biological endpoints reported.

Sample size: 14 vitamins
Population: In vitro vitamin analysis
Dosing: N/A
Duration: N/A
Route: N/A
Blinding: not_reported
Controls: none
Drug class: water-soluble vitamin

Full abstract

The fluorescence and phosphorescence characteristics of 14 vitamins were evaluated. The existence or absence of fluorescence and phosphorescence was compared with predictions based upon molecular structure. Analytically useful fluorescence signals were obtained for p-aminobenzoic acid, folic acid, calciferol, pyridoxine hydrochloride, riboflavine, alpha-tocopherol and vitamin A, whereas analytically useful phosphorescence signals were obtained for p-aminobenzoic acid, folic acid, niacinamide, pyridoxine hydrochloride, and alpha-tocopherol. All other vitamins either did not fluoresce or phosphoresce or could not be measured, owing to experimental difficulties. The complementary nature of fluorimetry and phosphorimetry is evident in these studies.

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