Magnesium basics.
Clinical kidney journal
confidence
Key findings
Review of magnesium's physiological role, absorption, excretion, and hypo-/hypermagnesaemia; no clinical/biological endpoints reported.
View source on PubMed (PMID 26069819) ↗
- Sample size
- Not applicable
- Population
- General population (review)
- Dosing
- Not applicable
- Duration
- Not applicable
- Route
- Not applicable
- Blinding
- not_reported
- Controls
- none
- Drug class
- mitochondrial peptide
Full abstract
As a cofactor in numerous enzymatic reactions, magnesium fulfils various intracellular physiological functions. Thus, imbalance in magnesium status-primarily hypomagnesaemia as it is seen more often than hypermagnesaemia-might result in unwanted neuromuscular, cardiac or nervous disorders. Measuring total serum magnesium is a feasible and affordable way to monitor changes in magnesium status, although it does not necessarily reflect total body magnesium content. The following review focuses on the natural occurrence of magnesium and its physiological function. The absorption and excretion of magnesium as well as hypo- and hypermagnesaemia will be addressed.