Three new isobenzofuranone derivatives from the fruiting bodies of Hericium erinaceus.
Journal of Asian natural products research
confidence
Key findings
Three new isobenzofuranone derivatives (erinaceolactones D-F) and four known isomers isolated from Hericium erinaceus fruiting bodies; structural elucidation via spectroscopy.
View source on PubMed (PMID 27243466) ↗
- Sample size
- Not reported
- Population
- Not applicable (chemical isolation study)
- Dosing
- Not reported
- Duration
- Not reported
- Route
- Not reported
- Blinding
- not_reported
- Controls
- none
- Drug class
- adaptogen
Full abstract
Three new isobenzofuranone derivatives erinaceolactones D-F (1-3), together with four known ones (4-7), were isolated from the fruiting bodies of Hericium erinaceus. Their structures were determined on the basis of comprehensive spectroscopic analyses including UV, 1D, 2D NMR and HR-TOF-MS. The absolute configuration of erinaceolactone D (1) and erinaceolactone E (2) were assigned by comparing their specific rotation with those of analogs in literatures. The four known compounds were isomers with each other and were isolated simultaneously for the first time.