NAD+observational1988
[Interaction of NAD-kinase with glutamate dehydrogenase].
Biokhimiia (Moscow, Russia)
confidence
Key findings
NAD kinase forms complexes with glutamate dehydrogenase; polymeric GDH involved; both oligomeric and monomeric NAD kinase forms can form complexes.
View source on PubMed (PMID 2827792) ↗
- Sample size
- N/A
- Population
- In vitro enzyme interaction study
- Dosing
- N/A
- Duration
- N/A
- Route
- N/A
- Blinding
- not_reported
- Controls
- none
- Drug class
- coenzyme
Full abstract
The formation of a NAD kinase-glutamate dehydrogenase complex was studied, using three independent methods. It was found that the polymeric form of glutamate dehydrogenase is involved in the formation of a complex with NAD kinase. Both the oligomeric and monomeric (subunit) forms of NAD kinase were shown to possess the ability to form complexes with glutamate dehydrogenase.