SpermidineanimalAnimal model1981
Polyamine metabolites and conjugates in man and higher animals: a review of the literature.
Physiological chemistry and physics
confidence
Key findings
Review of polyamine (putrescine, spermidine, spermine) metabolites and conjugates (acetylated, oxidized, protein-bound) in man and animals; no clinical/biological endpoints reported.
View source on PubMed (PMID 7010391) ↗
- Sample size
- Not applicable
- Population
- Man and higher animals (review)
- Dosing
- Not applicable
- Duration
- Not applicable
- Route
- Not applicable
- Blinding
- not_reported
- Controls
- not_reported
- Drug class
- polyamine
Full abstract
The current state of knowledge of the metabolic fate of the di- and polyamines putrescine, spermidine, and spermine is reviewed. Acetylated, oxidized, and protein-bound polyamines are found to be widely distributed in man and animals. The importance of understanding the roles of these compounds in health and disease is now recognized and is currently the subject of active research.